A multidisciplinary approach is a prerequisite for exact diagnosis

 

Because of the multiple organ systems involved and the variation of the age of onset, mitochondrial diseases may be difficult to be recognized. For exact diagnosis a collaboration of a multidisciplinary team of experts is necessary.

 

For further details see guidelines
 
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Diagnostic work up
Ergometry
Apparative diagnostics
Biopsy
Biochemical investigations
Morphology
Molecular genetics